University of Michigan

The University of Michigan is the top public university in research spending in the United States. Aligned with the goal of its Medical School, the Michigan Kidney Translational Medicine Center (MiKTMC) is centered on integrated systems biology analysis of kidney diseases. Leveraging and integrating multi-omic, morhpometric data, and longidtudinal clincial information drived from patients with various kidney diseases, MiKTMC is building a roadmap to implementing precision medicine in nephrology clinical practice.

People involved in Prime-CKD

Wenjun Ju

Wenjun Ju: PhD in molecular Biology. Lead contact of PRIME-CKD WP2. Dr. Ju is a Research Scientist in Department of Internal Medicine and Computational Medicine and Bioinformatics at UMICH. She has extensive experience in investigation of pathological mechanisms of CKD and non-invasive molecular mechanism-based biomarkers for kidney precision medicine. In PRIME-CKD, her responsibilities include leading the validation of the pharmacodynamic biomarkers in clinical trials (WP2) and working closely with colleagues from WP1 on the clinical-analytical evaluation of the biomarkers.

Matthias Kretzler

MD. Dr. Kretzler is the Warner-Lambert/Park-Davis Professor of Medicine and Director MiKTMC at the University of Michigan. Dr. Kretzler is the co-lead of WP2. He is the PI of the Nephrotic Syndrome Research Network (NEPTUNE) and the Kidney Precision Medicine Project. He integrated a kidney-specific research focus with the unique bioinformatic environment at UMICH for successful implementation of precision medicine strategies of renal diseases, from bioinformatic data mining to successful completion of targeted therapies in Phase II trials. In PRIME-CKD, Dr. Kretzler will provide oversight into data integration.

Viji Nair PhD

Dr. Nair is the lead bioinformatician/computational biologist on the MiKTMC at University of Michigan. Her research focus is in identifying non-invasive biomarkers and therapeutic targets predicting disease progression in Diabetic Nephropathy and CKD in general. Dr. Nair leads the bioinformatic efforts in multi-omics data integration by adapting a wide variety of established and novel computational approaches. In PRIME-CKD, Dr.Nair works in WP2 focusing on the investigation of molecular mechanisms underlying the biomarkers of interest with treatment response.

Emily Tanner

Emily Tanner received her Bachelor’s of Science from Michigan State University where she double majored in Genomics & Molecular Genetics and Microbiology with a specialization in Bioethics, Humanities, and Society. She joined MiKTMC in November 2017 and is now a Research Specialist. In PRIME-CKD, she is responsible for conducting biomarker measurements (WP2).

University of Michigan

People involved in Prime-CKD

Wenjun Ju

Matthias Kretzler

Viji Nair PhD

Emily Tanner

Links

EU FUNDING

CONTACT